Definition

(Adjective) Of persons or agents: Diligent, active, constant in application to the matter in hand; assiduous, persistent.

In Context

“But Somers, whose chronic maladies, aggravated by sedulous application to judicial and political business, made it necessary for him to avoid crowds and luxurious banquets, retired to Tunbridge Wells, and tried to repair his exhausted frame with the water of the springs and the air of its heath.”

Thomas Babington Macaulay, The History of England from the Accession of James the Second, Volume 5, 1861.